In another analysis of 89 EC patients, the aim was to assess the strength of various clinicopathological indicators for the prediction of treatment efficacy, and the results demonstrated no association between prognosis among ER, PAX2, PTEN or Ki-67 expression in the initially untreated AH or EEC groups, but expression >50% PR expression had the highest complete response in both the EEC and AH groups [71]. The gene discussed is PTEN; the disease is exstrophy-epispadias complex.