TNFRSF10B and acute lymphoblastic leukemia: In human acute lymphoblastic leukaemia cells, FBRE increased the expression of death-receptor-related proteins such as membrane-targeted death ligand (truncated Bcl-2 Homology 3 interacting-domain death agonist, tBid), death receptor-5 (DR5), and apoptosis antigen (Fas cell surface death receptor, Fas), while inhibiting the expression of an apoptosis inhibitor (B-cell lymphoma 2, Bc).