Recently, Pan et al. reported comparable performance for a molecular CXCL10 mRNA assay vs. T-Spot.TB in 352 patients with definite TB and 153 non-TB controls, with sensitivity of 93.9% vs. 94.5% and specificity of 98.0% vs. 100% for the diagnosis of Mtb infection. The gene discussed is CXCL10; the disease is tuberculosis.