Given that inflammatory states (a) involve interoceptive pathways [31], (b) are linked to the somatic symptom profile of atypical depression (e.g., leaden paralysis, hypersomnia) [14], but (c) are uncorrelated with dysfunctional self-reported interoception (as shown here for CRP), our findings contribute to a growing body of research that conceptualizes interoception as independent across submodalities at the perceptual level [24,61]. Here, CRP is linked to depressive symptom measurement.