The study examined if and how ten common variants in seven genes [BDNF (rs6265, chromosome 11p14), CACNA1C (rs1006737, chromosome 12p13), CRHR1 (rs12944712; chromosome 17q21), FKBP5 (rs1360780, rs9296158, and rs9470080, chromosome 6p21), OXTR (rs53576 and rs2254298, chromosome 3p25), RGS2 (rs4606, chromosome 1q31), SLC6A4 (variable number tandem repeat VNTR and rs25531, chromosome 17.q11–17.q12)] modified the associations between Hurricane Katrina exposure and development of PTG rather than PTSD in a sample of 205 low-income non-Hispanic Black people residing in New Orleans. Here, RGS2 is linked to post-traumatic stress disorder.