A study by Sonderstrup of 411 BRCA1/2mut early breast cancers showed that stromal TILs increasing in 10% intervals were significantly associated with OS (Hazard Ratio 0.92, 95% CI 0.84–1.00, p = 0.05) in BRCA1 and BRCA2mut breast cancers [122]. The gene discussed is BRCA1; the disease is breast carcinoma.