Additionally, a panel of EA PCa (22Rv1, LNCaP and PC-3) and AA PCa (RC77 T/E and MDA PCa 2b) cell lines were used as in vitro cell line models for evaluating the expression profiles and oncogenic properties of PIK3CD-L and PIK3CD-S in EA and AA PCa at the RNA level. The gene discussed is PIK3CD; the disease is posterior cortical atrophy.