CD8A and neoplasm: Thus, the migration of T-cells in ADC is lower than in SCC; this singular feature has been associated with a low expression of CXCL9, CXCL10, and CXCL11 in ADC compared with that of SCC and it is believed that this might be attributed to a greater presence of conventional type 1 DCs (cDC1) in SCC rather than in ADC, which is associated with a higher production of cytokines that stimulate the migration of cytotoxic CD8+ T-cells to the tumor [110].