Accordingly, in vitro study models showed that cervical cancer LCs stimulated with s-Poly-I:C have an increased expression of cell maturation markers (CD40, CD80, CD83, CD86, CCR7, MHC1, and MHCII), improved migration, and increased production of pro-inflammatory cytokines related to the stimulation of [cell-mediated cytotoxic response of CD8+ cells (IL-1beta, IL-6, IL-12p70, IP-10, TNF-alpha, IFNalfa, MCP-1, MIP-1alfa, MIP-1beta, and RANTES) [99]. The gene discussed is CD8A; the disease is cervical carcinoma.