PIK3CA and breast carcinoma: From this study, 17 significantly mutated genes were identified in human luminal breast cancer patients, including PIK3CA, TP53, GATA3, CDH1, RB1, MLL3, MAP3K1, CDKN1B, TBX3, RUNX1, LDLRAP1, STNM2, MYH9, AGTR2, STMN2, SF3B1, and CBFB.