From this study, 17 significantly mutated genes were identified in human luminal breast cancer patients, including PIK3CA, TP53, GATA3, CDH1, RB1, MLL3, MAP3K1, CDKN1B, TBX3, RUNX1, LDLRAP1, STNM2, MYH9, AGTR2, STMN2, SF3B1, and CBFB. Here, TP53 is linked to breast cancer.