IGF-1R was more expressed in patients with PCa compared to the BPH (100% vs. 0%); IGF-1R positivity was higher in Ki-67 + (78.6% vs. 45.5%) in INS R-α + (84.4% vs. 59.8%) and INSR-β + (9.4% vs. 1.5%) tissues. The gene discussed is IGF1R; the disease is posterior cortical atrophy.