The most common BRCA1 gene variants identified by whole exome sequencing in all our breast cancer cases were BRCA1 rs799917 C > T/c.2612C > T/p.Pro871Leu, BRCA1 rs1799966 T > C/c.4900A > G/p.Ser1634Gly/p.S1634G, BRCA1 rs1799949 G > A, c.2082C > T/p.Ser694/p.S694, BRCA1 rs1060915 A > G/c.4308T > C/p.Ser1436/p.S1436, and BRCA1 rs16940 A > G/c.2311T > C/p.Leu771/p.L771 (Supplementary Table S2). This evidence concerns the gene BRCA1 and breast cancer.