3.4. Comparative Analysis of the PI3K rs121913281 C > T, AKT-1 rs1130233 G > A, KLF 14 (rs972283 C > T), MDM4 rs11801299 A > G, miRNAs 27a rs895819A > G and miR-196a-2 rs11614913 C > T Genotypes in Breast Cancer Patients and Gender Matched Controls. The gene discussed is PIK3CA; the disease is breast cancer.