The dominant inheritance model showed a strong association between the MDM4-GG and (GA + AA) genotypes, which increases breast cancer susceptibility (OR = 2.15 (CI = 1.2010–3.8487), RR = 1.51 (1.0747–2.1247), and p = 0.010) (Table 7). This evidence concerns the gene MDM4 and breast carcinoma.