A strong correlation was reported in the recessive inheritance model between the PI3K –(CC + CT) and PI3K –TT genotypes and breast cancer susceptibility with an OR = 6.96, (95%) CI = 2.33–20.78, RR = 3.81, and p < 0.0005 (Table 6). The gene discussed is PIK3CG; the disease is breast carcinoma.