TGFB1 and ovarian carcinoma: In contrast, TGF-β upregulates CD103 (also known as integrin αEβ7 (ITGAE)) on CD8+ T cells infiltrating the tumor and malignant ascites, and by supporting the habitation of these cytotoxic T cells in the TME, they may represent a prognostic advantage in patients with ovarian cancer [327].