PPBP and cancer: In addition, platelets’ secretion of chemokines and cytokines, such as PF4 [70], CXCL7 (also known as neutrophil-activating peptide 2 (NAP-2)) [71], and TGF-β [191], following their interaction with cancer cells reinforces neutrophils’ attachment to the endothelium and their transendothelial migration.