Expression of eIF3d, eIF3e, eIF3f, eIF3h, and eIF3l correlates with the IDH-mutant status of gliomas. eIF3i and eIF3k expressions increase with tumour grade and are associated with poor OS. eIF3i is an independent prognostic factor in IDH-mutant LGG and can predict the 1p/19q codeletion status in IDH-mutant LGG. High eIF3i expression correlates with cell proliferation, mRNA processing, translation, T-cell receptor signalling, NF-kB signalling, and many others. The gene discussed is EIF3L; the disease is central nervous system cancer.