Interestingly, one peptide (m/z 1105.60) originating from phosphoprotein vinculin was found in high abundance in the tumor margins (Figure 5B), positively correlated with the defined cell–cell adhesion in VX2 tumors and often downregulated metastatic tumorigenesis and displaying the intermodulation between phosphorylation and O-GlcNAcylation [70,71,72]. Here, VCL is linked to neoplasm.