For example, CREBBP/EP300 gene mutations are frequently detected in diverse lymphomas, such as follicular lymphoma (FL) [39,40], DLBCL [16,42,43], in situ follicular neoplasia [44], peripheral T-cell lymphoma (PTCL) [37,45], angioimmunoblastic T-cell lymphoma (AITL) [37], and plasmablastic lymphoma (PBL) [46]. This evidence concerns the gene CREBBP and mature T-cell and NK-cell non-Hodgkin lymphoma.