HMOX1 and cancer: Recently, HMOX-1 induction was associated to the proliferation and invasivity of different human cancer cell lines cultured in low [Na+]: pancreatic adenocarcinoma (PANC-1), neuroblastoma (SK-N-AS, SH-SY5Y), colorectal adenocarcinoma (HCT-8), chronic myeloid leukaemia (K562) and SCLC (NCI-H69) cell lines [95,96].