Other natural compounds reported to induce PCa cell death by impairing mitochondrial functional plasticity and dynamics include atpenin A5 analogs (specific inhibitors of complex II activity) [303], jasmonates (inducers of mitochondrial ATP depletion) [304], alternol (inhibitor of TCA cycle, mitochondrial respiration and ATP production) [305] and deguelin (COI inhibitor) [306]. Here, MT-CO1 is linked to posterior cortical atrophy.