Further peptides that were included in the 181 Biomarker model and were also associated with disease progression originated from C-X-C motif chemokine 16 protein, protein S100-A9, matrix Gla Protein, fibrinogen alpha and fractalkine, confirmed with same trend of expression (i.e., elevated in PCa, or as disease progresses). This evidence concerns the gene MGP and posterior cortical atrophy.