Interestingly, while “positivity” in PD-1+ TILs alone was not associated with pCR, “co-positivities” of “CD20+ TILs plus PD-1+ TILs” and “CD20+ TILs plus PD-L1+ tumour cells” were significantly associated with high pCR rates (p = 0.04 and p = 0.005 respectively) [34]. This evidence concerns the gene CD274 and neoplasm.