In bladder cancer, HuR overexpression can promote bladder cancer proliferation, invasion, metastasis, and EMT by increasing the stability of polypyrimidine tract-binding protein 1 (PTBP1) to upregulate its expression [97], whereas destabilization of HuR causes a decrease in PTBP1 and inhibits bladder cancer progression [98]. The gene discussed is ELAVL1; the disease is urinary bladder cancer.