Certain RBPs play contrasting roles in a variety of different tumor cells, such as insulin-like growth factor 2 mRNA binding protein 1, also known as IMP1, which promotes colorectal cancer [12] and liver cancer [13] occurrence, progression, and metastasis; however, it can inhibit the proliferation and metastasis of breast cancer [14]. Here, IGF2BP1 is linked to colorectal cancer.