Up-regulated miR-494 destabilizes c-Myc mRNA and inhibits its translation, ultimately suppressing c-Myc-dependent matrix metalloproteinase (MMP)-2 expression, i.e., inhibiting bladder cancer proliferation and invasion via the HuR/JunB/miR-494/c-Myc/MMP-2 axis [101]. Here, MMP2 is linked to urinary bladder carcinoma.