The reasons for DO were (a) menopause in twenty-three patients, reaching the age of 50 in four patients, (b) other medical reasons in eleven patients (an increase in the CA125 in one patient, dysmenorrhea in three patients, metrorrhagia in four patients, ovarian cysts in two patients, and the presence of a P53 lesion on the surgical specimen in one patient), and (c) following the patient’s wishes in eight patients. The gene discussed is TP53; the disease is Ovarian cyst.