Furthermore, the knockdown of IQGAP3 also influenced a series of oncogenic mechanisms in ovarian cancer, as demonstrated by the alteration in the protein expression, including EMT-related proteins (E-CAD, N-CAD, ZEB-1, Vimentin, and Snail) and apoptosis-related proteins (Caspase-3, Caspase-9, Bcl2, and Bax) [45]. The gene discussed is IQGAP3; the disease is ovarian cancer.