When compared to a nonmalignant (NM) tissue, which includes normal adjacent tissue (NAT), hyperplasia and benign disease expression of NEDD9 increased from nonmalignant to invasive ductal carcinoma (IDC) and metastatic lesions (lymph node-Met/LN; Figure 1A-B). The gene discussed is NEDD9; the disease is invasive ductal breast carcinoma.