Downregulation of MVP is associated with an increased intracellular level of miR-193a that triggers cell cycle G1 arrest and impairs the growth of the human colon cancer SW620 in nude mice by targeting caprin-1 (cell cycle associated protein 1), an RNA binding protein that upregulates Ccnd2 and c-Myc [71]. This evidence concerns the gene CAPRIN1 and malignant colon neoplasm.