In fact, RT sustains CD8 T-cell recruitment into the tumor by inducing the expression of several factors, including IFNα, CXCL9, CXCL10, and CXCL11, as well as promoting extravasation by upregulating ICAM-1 and E-selectin on endothelial cells [17,22,23]. This evidence concerns the gene CD8A and neoplasm.