Upon multivariate COX regression analysis (stepwise method), the IL-6 levels (b coefficient = −0.0386; adjusted Exp(b) = 1.0388; 95%CI = 1.0230–1.0548; p < 0.0001) and miniCASCO-based cachexia severity (b coefficient = 0.2301; adjusted Exp(b) = 1.2587; 95%CI = 1.0850–1.4602; p = 0.0024) significantly affected PFS (Table 4). The gene discussed is IL6; the disease is Cachexia.