Most strikingly, our analysis revealed a seven-gene drug-tolerant signature in all four drug-tolerant cell lines, irrespective of chemotherapeutic treatment, parental cell line and tumour subgroup—LTBP1, MAP1A, MBNL2, LGALS1, PNRC1, DAB2 and PLAAT3 (Figure 5E). The gene discussed is PNRC1; the disease is neoplasm.