CD44 and cancer: According to other studies, CD44+/CD133+/EpCaM+ cells isolated from pancreatic cancer cell lines display a peculiar pattern of cancer stem cell-like characteristics [91], while in PDAC patients, the co-expression of CD133/CD44 in CSCs and CD204 in tumor-associated macrophages (TAMs) have been suggested as independent prediction markers for disease-free survival [92,93].