The median PFS in patients with PD-L1-positive tumours (63.2%) was 13.8 months (95% CI 11.1–not estimated) in the combination arm versus 7.2 months (95% CI 5.7–9.7 months) in the control arm (HR 0.61; 95% CI 0.47–0.79; p < 0.001). This evidence concerns the gene CD274 and neoplasm.