PIK3C2A and Muscle spasm: Other AEs reported in isolation were one grade 3 pneumonitis, one grade 3 creatine phosphokinase (CPK) elevation, one patient with grade 3 renal impairment, one patient with grade 3 muscle spasm, one episode of grade 2 mucositis, two patients with mild skin dryness/scaling, and one patient who presented with grade 1 hypoglycemia.