We found specifically increased class I (HDAC1, HDAC2) and class II (HDAC5, HDAC7, HDAC9, HDAC6, HDAC10) HDAC gene expression in AML patients compared to healthy controls and also confirmed the expression of these genes in various AML cell lines, representative of different AML subtypes. This evidence concerns the gene HDAC7 and acute myeloid leukemia.