Strikingly, we identified eight genes/proteins (AIP, NUDC, RPL35A, RPL37A, RPL6, RPS21, RPS25, and SMARCB1) that are overexpressed at the transcriptional level in AML patients but downregulated at the protein level upon TMP269 treatment in MOLM-13 cells (Figure 3A). The gene discussed is RPL35A; the disease is acute myeloid leukemia.