HDAC2 and acute myeloid leukemia: We observed significantly increased HDAC gene expression in samples from AML patients compared to healthy controls for HDAC1 and HDAC2 (class I HDACs, Figure 1B), as well as HDAC5, HDAC7, and HDAC9 (class IIA HDACs, Figure 1C), and HDAC6 and HDAC10 (class IIB HDACs, Figure 1D).