We observed significantly increased HDAC gene expression in samples from AML patients compared to healthy controls for HDAC1 and HDAC2 (class I HDACs, Figure 1B), as well as HDAC5, HDAC7, and HDAC9 (class IIA HDACs, Figure 1C), and HDAC6 and HDAC10 (class IIB HDACs, Figure 1D). Here, HDAC5 is linked to acute myeloid leukemia.