In addition to FGFR3, PIK3CA E545K (7.0%), E542K (4.4%), and H1047R (1.5%), ERBB2 S310F (4.6%), RXRA S427F (2.9%), and several TP53 recurrent mutations are frequently found in bladder cancers (Table S1). Here, PIK3CA is linked to urinary bladder carcinoma.