PIK3CA and cancer: The genes in which recurrent mutations were frequently observed were TP53 (8.7% in all cancer types), PIK3CA (7.9%), KRAS (6.6%), BRAF (5.8%), IDH1 (4.5%), NRAS (2.1%), FBXW7 (1.2%), PTEN (0.77%), CTNNB1 (0.77%), EGFR (0.64%), GTF2I (0.63%), AKT1 (0.52%), ERBB2 (0.51%), and FGFR3 (0.45%).