We further investigated whether either low or high CXCR3 expression was associated with cell density of CD8, CD4, CD68 and FoXP3 expression in tumor infiltrating lymphocytes (TILs) and found a significant correlation between CD8+ T cell infiltration and CXCR3high tumors (p < 0.0001) compared to CXCR3low tumors, Figure 5A. CD4 (Figure 5B) and CD68 (Figure 5C) were found to be higher expressed in case of an underlying CXCR3high tumor, yet without statistical significance. Here, CD4 is linked to neoplasm.