CXCR3 and neoplasm: We further investigated whether either low or high CXCR3 expression was associated with cell density of CD8, CD4, CD68 and FoXP3 expression in tumor infiltrating lymphocytes (TILs) and found a significant correlation between CD8+ T cell infiltration and CXCR3high tumors (p < 0.0001) compared to CXCR3low tumors, Figure 5A. CD4 (Figure 5B) and CD68 (Figure 5C) were found to be higher expressed in case of an underlying CXCR3high tumor, yet without statistical significance.