Patients with active IgG4-RD showed higher numbers of Tfh17 (p = 0.03), Tr1 (p < 0.001), Th3 (p = 0.02), pDC IL-10+ (p = 0.009), M2 (p = 0.04), and M1 monocytes (p = 0.02), compared with patients with inactive disease (Figure 1; Supplementary Table S5). Here, IL10 is linked to immunoglobulin G4-related sclerosing disease.