The analysis of TFAP2D gene in LUAD subtype (Figure 3D) revealed that significantly lower expression level was observed at stage 4 of LUAD vs. stage 1 (p < 0.001), stage 2 (p = 0.0063) and stage 3 (p = 0.0068), which may indicate inhibition of TFAP2D gene expression along with tumor development. The gene discussed is TFAP2D; the disease is neoplasm.