STAT1 and neoplasm: Additionally, STAT1 deficiency leads to decreased production of C-X-C motif chemokine receptors (CXCL9, CXCL10, and CXCL11) in the tumor epithelium, all of which work as T-cell chemotactic factors, suggesting STAT is an important contributor to DOX’s effects on the antitumor immune response [268].