The components of chromatin-remodeling complexes encoded by ZNF335 and PHC1, the components of the condensin complex encoded by NCAPD2, NCAPH, and NCAPD3, as well as the pre-mRNA-processing spliceosome component encoded by the SNRPE gene represent regulators of mitotic division and their dysfunction in early development, are associated with microcephaly [33,51,70,71]. Here, SNRPE is linked to microcephaly.