A large inversion of size 20 Mbp was observed at 11q12-q14 in the five DLBCL cell lines OCI-LY1, NU-DHL-1, SU-DHL-6, DOHH-2, and SU-DHL-9 and encompassed three oncogenes (CCND1, MALAT1, NUMA1) and two TSGs (MEN1, SDHAF2). Here, CCND1 is linked to diffuse large B-cell lymphoma.