CXCL8 and glioblastoma: In addition, CP-DN-ATF5 suppressed expression of the CEBPB and CEBPD targets IL6 and IL8 in T98G and LN229 GBM cells as well as in WT and ATF5- HAP1 cells, and significantly reduced CEBPB and CEBPD occupancy of the IL6 and IL8 promoters in T98G cells.