ASNS and central nervous system cancer: Moreover, consistent with interference with CEBPB, CEPBD and ATF5 activities, in T98G and other non-glioma cancer lines, Dpep and Bpep suppressed expression of direct CEBPB/CEBPD targets IL6 and IL8 and of direct ATF5 and CEBPB target asparagine synthetase (ASNS).