Using si- and shRNAs that had been developed [22] to study ATF5′s role in neuroprogenitor cell growth and differentiation, Angelastro et al. [30] knocked down ATF5 in a rat (C6) and 4 human (U251, U138, U373 and T98G) GBM cell lines. This evidence concerns the gene ATF5 and glioblastoma.