Two of these SNPs were in the BCL2 gene and were protective against AKI: rs8094315 (odds ratio [OR] 0.61 per additional copy of the minor G allele, p = 0.016) and rs12457893 (OR 0.71 per additional copy of the minor C allele, p = 0.026 in validation set). The gene discussed is BCL2; the disease is acute kidney injury.