IDUA and mucopolysaccharidosis type 1: Other human AEC transplantation studies achieved reduced liver fibrosis in CCl4-treated immunocompetent C57BL/6 mice [54,55] or restored the glycosaminoglycan (GAG)-degrading enzyme α-l-iduronidase (IDUA) function in the livers of mucopolysaccharidosis type 1 (MPS1) NOD.129(B6)-Prkdcscid Iduatm1Clk mice [56].