↓ level of GH is associated withsteatosis grade 2–3 (univariate RR = 0.196; multivariate RR = 0.199)↓ level of IGF-1 is associated with fibrosisGH/IGF-1 ratio is significantly lower in patients with steatosis grade 2–3 compared to those with grade 1 No significant difference in GH/IGF-1 ratio among different grades of steatosis. This evidence concerns the gene GH1 and steatosis.