CDK19 and pachyonychia congenita: Wen et al. reported that high N6-methyladenosine (m6A) levels in NEAT1 enhanced cyclin L1 (CCNL1) and cyclin-dependent kinase 19 (CDK19) binding, increasing DNA polymerase II (Pol II) Ser2 phosphorylation and promoting PC-associated-bone metastasis, and correlated with poor PC prognosis [45].