The tumor-promoting role of autophagy in breast cancer carcinogenesis and cell proliferation includes increased glycolysis, increased cyclin D1 expression, RAS pathway, mitogen-activated protein kinase (MAPK)/ nuclear factor erythroid 2-related factor 2 (NRF2) pathway, Src family of protein tyrosine kinases (SRC) pathway, and integrin β1 signaling [44]. The gene discussed is NFE2L2; the disease is breast cancer.