NTS and hepatocellular carcinoma: Similarly, rare genetic variants in telomerase reverse transcriptase (TERT) rs2242652 C > T, TP53, apolipoprotein B (APOB), proline/serine-rich coiled-coil protein 1 (PSRC1) rs599839 A > G, and neurotensin (NTS) rs1800832 A > G have been outlined as possible modifiers of the genetic risk of HCC, irrespective of the fibrosis severity [99,100,101,102].