VWF and Skin rash: We found that skin involvement at specific focal points (i.e., a joint-related skin rash) had a 46% increased odds of higher vWF:Ag levels (p = 0.013), generalized skin involvement had 158% increased odds (p = 0.006), and eyelid peripheral blood vessel dilation had 32% increased odds (p = 0.036) (Table 3).