TYRP1 and neoplasm: Since then, the role of CatB in the antitumor immune response has been shown to be related to the processing of antigens [89]; reduced persistence of cytotoxic CD8+ T cells [90]; infiltration of immunosuppressive immune cells, such as tumor associated macrophages (TAM); myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs) in gliomas [91] and pancreatic ductal adenocarcinoma [92].