KRAS and malignant colon neoplasm: Mut3DPTSh1-Ras was then assayed for its ability to induce cancer cell death in a number of different cancer cell lines and was found to induce significant apoptosis in MDA-MB-231 breast cancer, SW626 ovarian cancer, SW480 colon cancer and HBCx17 breast cancer cell lines, but only minimally affected the cell viability of HCT-116 and HT-29 colon cancer cell lines, even though they carry K-ras mutations [28].