STEAP1 and cancer: A mixed Th1/Th2 profile is in line with observations we have previously made for T cells transduced with tumor-targeting TCRs [38,39] or the JK11 STEAP1 CAR [22] and in studies of cancer vaccine responses [40,41], where a strict Th1/Th2 dichotomy did not apply even in monoclonal T cell cultures [42].