For cytokines mostly associated with adaptive lymphocyte responses, including; IL-2 (2.052 (1.391) vs. 0.525 (1.404) pg/mL, p = 0.03); IL-12p70 (5.989 (1.332) vs. 1.954 (1.342) pg/mL, p = 0.04); IL-4 (3.456 (1.432) vs. 0.669 (1.445) pg/mL, p = 0.01); and, IL-13 (1.747 (1.568) vs. 15.502 [1.551] pg/mL, p = 0.005), these were significantly elevated in AU cases with GI symptoms compared to those AU cases without GI symptoms. This evidence concerns the gene IL2 and alopecia universalis congenita.